{"id":829,"date":"2020-11-16T09:23:55","date_gmt":"2020-11-16T14:23:55","guid":{"rendered":"https:\/\/covidqanda.org\/?p=829"},"modified":"2020-11-16T09:23:55","modified_gmt":"2020-11-16T14:23:55","slug":"how-can-someone-that-close-to-a-sick-person-not-get-it","status":"publish","type":"post","link":"https:\/\/covidqanda.org\/?p=829","title":{"rendered":"How can someone that close to a sick person not get it?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong><u>Question:<\/u><\/strong>\u00a0\u00a0A friend of mine told me yesterday that her mom (age 75, but generally healthy) had covid last month (confirmed with 2 trips to the dr, a test and lost sense of taste as well as fever and lethargy, but recovered after 2 weeks with no remaining symptoms), but that her dad, who slept in the same bed with her mom every night and took care of her mom, never got it (he was tested twice). How can someone that close to someone sick not get it?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">Answer:\u00a0<\/span><\/strong>Great question that scientists are still trying to answer!\u00a0 Short answer== The odds that your friend&#8217;s dad would have contracted COVID are high, but infection is not a certainty.\u00a0\u00a0<br><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><em>What are the odds of infection?<\/em><\/strong> As stated above, we don&#8217;t fully know the odds,\u00a0but they are high, especially given the circumstances you describe.\u00a0 Recent findings published in CDC&#8217;s <em>MMWR,\u00a0<\/em><a href=\"https:\/\/www.cdc.gov\/mmwr\/volumes\/69\/wr\/mm6944e1.htm#:~:text=The%20rates%20of%20symptomatic%20and,%25%E2%80%9324%25)%2C%20respectively\">Transmission of SARS-COV-2 Infections in Households<\/a>, conclude that &#8220;transmission of SARS-CoV-2 among household members was frequent from either children or adults&#8221; with the secondary infection rate among household members ages 50+ being 62% (95% CI: 44%-77%).\u00a0 Restated, this study found that 3 in 5 household members ages 50+ contracted COVID from their household member.\u00a0 Now, these data aren&#8217;t meant to be extrapolated to the broader population, but I&#8217;m sharing them here to reinforce the point that the odds are high.\u00a0 A paper <a href=\"https:\/\/aip.scitation.org\/doi\/10.1063\/5.0025476\">published last month in <em>Physics of Fluid<\/em><\/a>\u00a0aims to mathematically model infection risk and numerous other scientists are working on similar endeavors.\u00a0\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><br><strong><em>Why isn&#8217;t infection a certainty?<\/em><\/strong> When it comes to COVID, there are <a href=\"https:\/\/aip.scitation.org\/doi\/10.1063\/5.0025476\">many factors<\/a> influencing transmission (<strong>Figure 1<\/strong>).\u00a0 The three main buckets are: 1) amount of virus expelled by the infected host; 2) environmental factors that allow the virus to transport to susceptible host; 3) amount of virus inhaled by susceptible host.\u00a0 But what influences these pathways, especially the infected host factors and susceptible host factors, is still not fully known.\u00a0 When it comes to infected host:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>&#8220;A growing number of studies estimate that a majority of infected people may not infect a single other person. <a href=\"https:\/\/www.nature.com\/articles\/s41591-020-1092-0\">A recent paper<\/a> found that in Hong Kong, which had extensive testing and contact tracing, about 19 percent of cases were responsible for 80 percent of transmission, while 69 percent of cases did not infect another person. This finding is not rare: <a href=\"https:\/\/www.nature.com\/articles\/s41591-020-1092-0\">Multiple studies<\/a> from the <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7185944\/\">beginning<\/a> have suggested that as few as 10 to 20 percent of infected people may be responsible for as much as 80 to 90 percent of transmission, and that <a href=\"https:\/\/arxiv.org\/pdf\/2005.13689.pdf\">many people barely transmit it<\/a>.&#8221; -Zeynep Tufekci,&nbsp;<em><a href=\"https:\/\/www.theatlantic.com\/health\/archive\/2020\/09\/k-overlooked-variable-driving-pandemic\/616548\/\">The Atlantic<\/a><\/em><\/p><\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">As <a href=\"https:\/\/www.pbs.org\/newshour\/science\/why-understanding-superspreaders-is-key-to-controlling-covid-19\">described in a PBS report<\/a> last month:<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\"><p>&#8220;&#8216;It is clear that there are some people who, because of their own personal biology \u2014 we don\u2019t know enough about it yet \u2014 they produce a higher percentage of aerosols versus respiratory droplets&#8217; [said Dr. Crystal Watson, a public health preparedness expert at the Johns Hopkins Center for Health Security] &#8230;. &#8216;One possibility is that different individuals have respiratory fluid with different viscosity and interfacial tension, both of which affect the dynamics of droplet formation.&#8217; [said Professor William Ristenpart, a chemical engineer at University of California, Davis]\u201d<\/p><\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Figure 1. Factors influencing COVID transmission\/infection <\/strong>(from <a href=\"https:\/\/hub.jhu.edu\/2020\/10\/21\/contagion-airborne-transmission-inequality\/?mc_cid=1ad2288cfb&amp;mc_eid=3ad20857c3&amp;utm_source=Global+Health+NOW+Main+List&amp;utm_campaign=53c7d310f1-EMAIL_CAMPAIGN_2020_10_23_04_55&amp;utm_medium=email&amp;utm_term=0_8d0d062dbd-53c7d310f1-870311\">Johns Hopkins<\/a>)<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"2241\" height=\"1457\" src=\"https:\/\/i2.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?fit=723%2C470&amp;ssl=1\" alt=\"\" class=\"wp-image-830\" srcset=\"https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?w=2241&amp;ssl=1 2241w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?resize=300%2C195&amp;ssl=1 300w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?resize=1024%2C666&amp;ssl=1 1024w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?resize=768%2C499&amp;ssl=1 768w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?resize=1536%2C999&amp;ssl=1 1536w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?resize=2048%2C1332&amp;ssl=1 2048w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?w=1446&amp;ssl=1 1446w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?w=2169&amp;ssl=1 2169w\" sizes=\"auto, (max-width: 723px) 100vw, 723px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Question:\u00a0\u00a0A friend of mine told me yesterday that her mom (age 75, but generally healthy) had covid last month (confirmed with 2 trips to the dr, a test and lost sense of taste as well as fever and lethargy, but recovered after 2 weeks with no remaining symptoms), but that her dad, who slept in [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":830,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[38,93,60,18],"tags":[150],"class_list":["post-829","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-immunity","category-models","category-risk","category-transmission-routes","tag-viral-load","fallback-thumbnail"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2020\/11\/image-2.png?fit=2241%2C1457&ssl=1","_links":{"self":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/829","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=829"}],"version-history":[{"count":1,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/829\/revisions"}],"predecessor-version":[{"id":832,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/829\/revisions\/832"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/media\/830"}],"wp:attachment":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=829"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=829"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=829"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}