{"id":1638,"date":"2021-10-14T08:54:38","date_gmt":"2021-10-14T12:54:38","guid":{"rendered":"https:\/\/covidqanda.org\/?p=1638"},"modified":"2021-10-14T08:54:38","modified_gmt":"2021-10-14T12:54:38","slug":"are-antigen-tests-a-good-option-for-my-wedding-guests","status":"publish","type":"post","link":"https:\/\/covidqanda.org\/?p=1638","title":{"rendered":"Are antigen tests a good option for my wedding guests?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">Question:<\/span><\/strong>\u00a0I\u2019m having my wedding in a few weeks and we have asked guests to take a covid test 72 hrs prior (in addition to other precautions). A few guests have pointed out updated information on rapid antigen tests. While I know pcr is the gold standard, I wonder about the use of rapid antigen tests for those who don\u2019t have 3 days between travel and the event. Any thoughts?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">Answer:\u00a0<\/span><\/strong>Congratulations on your upcoming wedding! When it comes to testing, you&#8217;re right that PCR testing is more precise than antigen testing.\u00a0 Generally, antigen tests are pretty good at identifying cases in the early symptomatic\u00a0period (see\u00a0<a href=\"https:\/\/covidqanda.org\/?p=89\">Q&amp;A of 10\/24\/20<\/a>), but not as good as PCR at picking up cases during early infection and 1+ week after infection.\u00a0 Even so, antigen tests could be a great addition to your medley of public health precautions.\u00a0 If I were you, I&#8217;d add antigen tests as an option for guests to use, with the push that they get tested twice&#8211; 3 days before the wedding and the morning of the wedding.\u00a0 And if anyone has had a known exposure or symptoms, I&#8217;d ask that they stick with the PCR test (although for someone with symptoms, I&#8217;d probably ask that they not come!). On this front, if time is of the essence, it&#8217;s good to remember there are a few sites that offer\u00a0<a href=\"https:\/\/covidqanda.org\/?p=13\">rapid molecular tests<\/a>, which are quick turn-around tests that are provider-administered with sensitivity rates similar to PCR.\u00a0If you want to read more on rapid antigen tests, here are a few relevant details:\u00a0 \u00a0\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A\u00a0<a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06528-3\">recent systematic analysis<\/a>\u00a0published in\u00a0<em>BMC Infectious Diseases,\u00a0<\/em>which synthesized results of 24 published studies, found that sensitivity*&#8211; the ability of a test to pick up all cases&#8211; of lateral flow assays (a type of antigen rapid test) varied dramatically by test type (<strong>Figure 1<\/strong>). Authors noted,\u00a0&#8220;BD Veritor had the best sensitivity of 99.19% (95% CI 95.54\u201399.86%), though the sample size was small and it was only tested from a single centre study&#8230;. Panbio Abbott has been most thoroughly evaluated and noted a sensitivity of 78.41% (95% CI 76.78\u201379.96%) across over 2500 individual tests.&#8221;\u00a0 Other research has shown that\u00a0<a href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2782881\">sensitivity of antigen tests can be greatly increased<\/a>\u00a0 if they are used every 3 days (reaching 98% in a small study). Many test kits that you can purchase at the drug store come with 2 tests, so this type of serial testing can be done with just one purchase. Finally, two days ago\u00a0<em>Scientific American<\/em>\u00a0published an article that is really informative and easy to read on this topic,\u00a0<a href=\"https:\/\/www.scientificamerican.com\/article\/the-smartest-way-to-use-rapid-at-home-covid-tests1\/\">The Smartest Way to Use Rapid At-Home COVID Tests<\/a>.<br><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">*For a refresh of sensitivity\/specificity, see\u00a0<a href=\"https:\/\/covidqanda.org\/?p=629\">Q&amp;A of 4\/15\/20<\/a>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Figure 1. Sensitivity of different types of rapid tests\u00a0<\/strong>(from\u00a0<em><a href=\"https:\/\/bmcinfectdis.biomedcentral.com\/articles\/10.1186\/s12879-021-06528-3\">BMC Infectious Diseases<\/a>)<\/em><\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img data-recalc-dims=\"1\" loading=\"lazy\" decoding=\"async\" width=\"723\" height=\"367\" src=\"https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/10\/image-5.png?resize=723%2C367&#038;ssl=1\" alt=\"\" class=\"wp-image-1639\" srcset=\"https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/10\/image-5.png?resize=1024%2C520&amp;ssl=1 1024w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/10\/image-5.png?resize=300%2C152&amp;ssl=1 300w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/10\/image-5.png?resize=768%2C390&amp;ssl=1 768w, https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/10\/image-5.png?w=1401&amp;ssl=1 1401w\" sizes=\"auto, (max-width: 723px) 100vw, 723px\" \/><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Question:\u00a0I\u2019m having my wedding in a few weeks and we have asked guests to take a covid test 72 hrs prior (in addition to other precautions). A few guests have pointed out updated information on rapid antigen tests. While I know pcr is the gold standard, I wonder about the use of rapid antigen tests [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1640,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[17,6],"tags":[9,41,11],"class_list":["post-1638","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-risk-reduction","category-testing","tag-antigen-tests","tag-pcr","tag-sensitivity","fallback-thumbnail"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/10\/pexels-photo-1779414.jpeg?fit=1880%2C1253&ssl=1","_links":{"self":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/1638","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1638"}],"version-history":[{"count":1,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/1638\/revisions"}],"predecessor-version":[{"id":1641,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/1638\/revisions\/1641"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/media\/1640"}],"wp:attachment":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1638"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1638"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1638"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}