{"id":1433,"date":"2021-06-15T08:28:46","date_gmt":"2021-06-15T12:28:46","guid":{"rendered":"https:\/\/covidqanda.org\/?p=1433"},"modified":"2021-06-15T08:28:46","modified_gmt":"2021-06-15T12:28:46","slug":"how-long-lasting-is-immunity-after-infection","status":"publish","type":"post","link":"https:\/\/covidqanda.org\/?p=1433","title":{"rendered":"How long-lasting is immunity after infection?"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong><span style=\"text-decoration: underline;\">Question:<\/span><\/strong>\u00a0I had coffee the other day with a former colleague.\u00a0 He was telling me that his wife had COVID in February 2020 and that as a result, she doesn&#8217;t need to get the vaccine.\u00a0 Is she immune to COVID for life?<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><span style=\"text-decoration: underline;\"><strong>Answer:<\/strong><\/span>\u00a0Duration of immunity is another area that we&#8217;re still learning about.\u00a0 I&#8217;ve included more details below, but to sum up, immunity post-infection could be long-lived for many, but not all individuals.\u00a0 Immunity will be greatly enhanced through vaccination, which CDC and other\u00a0experts recommend.\u00a0 Read on for more details.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When it comes to <strong>immunity post-infection<\/strong>, we know that:\u00a0<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Infection-derived immunity (aka natural immunity) is more heterogeneous than vaccine-derived immunity, varying especially by age and by severity of infection. (see <a href=\"https:\/\/apps.who.int\/iris\/rest\/bitstreams\/1346855\/retrieve\">WHO<\/a>, <a href=\"https:\/\/covidqanda.org\/?p=1234\">Q&amp;A of 3\/18\/21<\/a>)<\/li><li>In most people, immunity lasts at least 6-8 months (as long as we have solid longitudinal&nbsp;data), and likely much longer. (see <a href=\"https:\/\/apps.who.int\/iris\/rest\/bitstreams\/1346855\/retrieve\">WHO<\/a>)&nbsp;&nbsp;<\/li><li>Recent research indicates that long-term immunity to SARS-CoV-2 may persist for years.&nbsp; For example, a <a href=\"https:\/\/www.nature.com\/articles\/s41586-021-03647-4\">paper published in <em>Nature<\/em><\/a>&nbsp;last month found that SARS-CoV-2 infection induces long-lived immune memory residing in bone marrow (home of memory B cells). (for more on this topic, see this <a href=\"https:\/\/www.nature.com\/articles\/d41586-021-01557-z\">commentary published in <em>Nature <\/em>just yesterday<\/a> and for&nbsp;a quick refresh on how the immune system works, see&nbsp;<a href=\"https:\/\/covidqanda.org\/?p=546\">Q&amp;A of 5\/9\/20<\/a>).<\/li><li>Even in this study, however, immunity was not consistent across study participants; of those participants who donated bone marrow (n=19), four (4) did not have detectable&nbsp;memory B cells.&nbsp; As the lead study author, <a href=\"https:\/\/www.nytimes.com\/2021\/05\/26\/health\/coronavirus-immunity-vaccines.html\">Dr. Ellebedy, told the <em>New York Times<\/em>,<\/a> &nbsp;\u201cIt tells me that even if you got infected, it doesn\u2019t mean that you have a super immune response. The findings reinforce the idea that people who have recovered from Covid-19 should be vaccinated.&#8221;&nbsp;<\/li><li>Among individuals who had been previously infected, vaccination with mRNA vaccines has been <a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2021.05.07.443175v2\">shown to further boost immune response<\/a>.&nbsp;&nbsp;<\/li><li><a href=\"https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/vaccines\/faq.html\">CDC recommends<\/a> that individuals should be vaccinated regardless of whether they already had COVID-19.<\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Question:\u00a0I had coffee the other day with a former colleague.\u00a0 He was telling me that his wife had COVID in February 2020 and that as a result, she doesn&#8217;t need to get the vaccine.\u00a0 Is she immune to COVID for life? Answer:\u00a0Duration of immunity is another area that we&#8217;re still learning about.\u00a0 I&#8217;ve included more [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1434,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[50,38,64],"tags":[210],"class_list":["post-1433","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-guidelines","category-immunity","category-vaccines","tag-natural-immunity","fallback-thumbnail"],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/i0.wp.com\/covidqanda.org\/wp-content\/uploads\/2021\/06\/pexels-photo-4418992.jpeg?fit=1880%2C1253&ssl=1","_links":{"self":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/1433","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1433"}],"version-history":[{"count":1,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/1433\/revisions"}],"predecessor-version":[{"id":1435,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/posts\/1433\/revisions\/1435"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=\/wp\/v2\/media\/1434"}],"wp:attachment":[{"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1433"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1433"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/covidqanda.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1433"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}